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VGSC DISCOVERY AND STRUCTURE
Contents:
  1. Sodium channel
  2. Veratridine modifies the gating of human voltage-gated sodium channel Nav1.7
Action Potentials 2 - Voltage-Gated Ion Channels

GO voltage-gated sodium channel complex. By sequence By domain architecture.

Proteins matched Domain architectures Literature 5. Add your annotation Add your annotation. Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene family.

Sodium channel

Sato C, Matsumoto G. Proposed tertiary structure of the sodium channel.

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature Contributing signatures Signatures from InterPro member databases are used to construct an entry.

References

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We have a dedicated site for Germany. A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior.


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Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function.

Veratridine modifies the gating of human voltage-gated sodium channel Nav1.7

This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied. JavaScript is currently disabled, this site works much better if you enable JavaScript in your browser.

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